A candidate list needs evaluation
A proposed candidate is not yet a measured biological outcome.
AMDE + ALCHEMI supplies physics-grounded scoring through GPU molecular dynamics for the defined discovery workflow.
Synthesis / Layer 1 / BSPINFORGE / A GARMO LABS COMPANY
AMDE + ALCHEMI
Physics-grounded drug-discovery scoring through GPU molecular dynamics.
Customer outcomeDesign and discover ↗
THE PRODUCT, IN PRACTICE
Evaluate the candidate.
Bring physics into view.
Candidate generation and candidate evaluation are different responsibilities. AMDE + ALCHEMI brings GPU molecular dynamics into drug-discovery scoring. AMDE is powered by SpinForge Discovery Core; the combined family entry is counted once in the eleven-product synthesis family.
- BUILT FOR
- Computational drug-discovery teams evaluating candidates with physics-based models.
CHALLENGES → PRODUCT RESPONSEThe problem you face.
The problem you face.
What the product changes.
YOUR CHALLENGEWITH AMDE + ALCHEMI
The model determines the score’s meaning
A numerical score is only interpretable with its target, simulation assumptions and evaluation conditions.
Scope the modeled system and scoring comparison so the result can be evaluated alongside other candidate evidence.
Shared technology can become invisible
Separate application names can hide the computational foundation they share.
AMDE’s named engine is SpinForge Discovery Core, also used by SpinForge Bio. Application-specific evaluation remains separate.
WHAT YOU GETA defined capability.
A defined capability.
A useful result.
Physics-grounded scoring
GPU molecular-dynamics-based scoring for drug-discovery work.
A candidate-evaluation role
A distinct contribution from merely generating candidate sequences.
Shared Discovery Core
AMDE uses the same named foundation as SpinForge Bio.
An agreed research workflow
Define inputs, modeled conditions, outputs and acceptance before the engagement.
EXPLICIT DEPENDENCY
AMDE uses Discovery Core.
AMDE + ALCHEMI remains one Layer 1 family entry. The owner’s clarified dependency is AMDE → SpinForge Discovery Core.
Explore the shared engineEXAMPLE CUSTOMER WORKFLOW
Evaluate a computational candidate set
A research team wants to compare candidate behavior under an agreed physical model.
Illustrative customer use—not a new benchmark or completed customer deployment.- 01→
Provide the modeled system, candidates and evaluation objective.
- 02→
Use the supported GPU molecular-dynamics scoring workflow.
- 03→
Review the computational scores with their assumptions and downstream validation plan.
FIT & ACCEPTANCEStart with the task.
Start with the task.
Agree the useful outcome.
- What you bring
- The target/system representation, candidate inputs, modeled conditions and scoring objective.
- What a useful evaluation measures
- +Numerical and model consistency
- +Repeatability under the agreed conditions
- +Relevance to the downstream research question
- Delivery
- License the selected capability, commission an implementation, or agree an operated service. Infrastructure and additional engineering are specified separately.
QUESTIONS BEFORE BUYINGA clear scope.
A clear scope.
A clear relationship.
What is the important boundary?−
Computational scoring is not evidence of experimental binding, efficacy, toxicity or clinical suitability. Discovery Core is explicitly the engine behind AMDE; no separate unprovided ALCHEMI dependency is invented.
How is it priced?+
No new standalone price is supplied for this product; request a scoped proposal. The platform plans buy qualified workflows and capacity, not a second charge every time a compatible method is selected. Existing bundle inclusions do not expand automatically.
How do we get access?+
An existing product in the SpinForge portfolio. Request the release, available invocation interfaces and setup for your selected workflow; this publication does not invent executable commands or MCP tool names.
PUT THE PRODUCT TO WORK
Tell us what needs to improve.
Bring a task, an accepted outcome and the environment in which the product needs to work.
PRODUCT RELATIONSHIPS
Related, not interchangeable.
SpinForge Discovery Core
The shared computational engine behind AMDE and SpinForge Bio.
SpinForge Bio
Protein binder design producing a ranked candidate panel for downstream synthesis and evaluation.
GARMO Scientist
An autonomous discovery product organized around perceive → hypothesize → experiment → learn.
ONE PLATFORM
Choose a qualified workflow.
Select the capability you need directly or include its compatible role in a qualified platform workflow. Production scope identifies release, environment, capacity and support; a product count is not an entitlement.
Explore monthly plans See the system connectionsSTART WITH THIS PRODUCT
Use the software directly or ask us to scope the implementation.